This study examines the role of family history in Parkinson disease, comparing demographic and clinical features between familial and sporadic cases.

This article explores the challenges and debates surrounding psychiatric diagnosis, including DSM, ICD, HiTOP, and alternative classification models. It provides insights into diagnostic pluralism and offers guidance for clinicians navigating multiple diagnostic frameworks.

This study demonstrates the extensive flow of cerebrospinal fluid (CSF) throughout the peripheral nervous system, challenging traditional views of CSF restriction. The research has implications for neural drug delivery and CNS/PNS therapy.

This article establishes clinical criteria for a limbic-predominant amnestic neurodegenerative syndrome (LANS). The study explores its relationship with limbic-predominant age-related TDP-43 encephalopathy and Alzheimer's disease, providing diagnostic guidelines.

This article reviews the epidemiology, pathophysiology, and current approaches to diagnosing autoimmune neurological disorders. It covers antibody biomarkers, immunotherapy, and recent clinical trials.

This study develops a clinical suspicion index for secondary schizophrenia spectrum disorders using expert consensus via the Delphi method, improving early detection and differentiation from primary schizophrenia.

This review explores the pathophysiology and diagnosis of MOG antibody-associated disorder (MOGAD), differentiating it from neuromyelitis optica and multiple sclerosis.

This study examines treatment outcomes for inpatients with severe functional neurological disorder (FND), highlighting the efficacy of multidisciplinary rehabilitation.

This article outlines the core curriculum for training in Behavioral Neurology & Neuropsychiatry, providing a structured approach to integrating these historically parallel disciplines.

This review examines cranial functional movement disorders, covering their clinical features, differential diagnosis, and the importance of early recognition for effective treatment.

This study investigates the clinical and imaging characteristics of globular glial tauopathy (GGT) and how they differ from other tauopathies like PSP and CBD.

This study examines associations between COVID-19 and subsequent mental illnesses by vaccination status, utilizing data from over 18 million individuals in England. It highlights the mitigating effect of vaccination on mental health outcomes following infection.

This study characterizes DPPX antibody–associated encephalitis, a condition linked to CNS hyperexcitability, weight loss, and cognitive impairment. It examines immunotherapy responses and potential antibody-mediated pathophysiology.

This historical review examines a rare film made by Samuel Alexander Kinnier Wilson in the mid-1920s, documenting patients with movement disorders. The film showcases conditions such as Parkinson's disease, Huntington's chorea, Sydenham's chorea, multiple sclerosis, and Wilson's disease.

This review covers the latest developments in autoimmune encephalitis (AIE), discussing its psychiatric implications, diagnostic criteria, and treatments. It highlights the role of the immune system in psychiatric disorders and the importance of early diagnosis.

This article provides an updated definition of Long Covid by the National Academies of Sciences, Engineering, and Medicine, emphasizing clinical manifestations, diagnosis, and long-term impact.

This study investigates how major stress in early childhood affects brain-immune signaling, linking inflammation and corticostriatal responsivity to reward processing.

This systematic review examines fMRI studies on self-disturbance in schizophrenia, analyzing altered neural correlates of self-processing.

This review discusses glutamatergic modulators in treating major depression, focusing on NMDA-targeted therapies like ketamine and esketamine.

This paper explores ancient Babylonian descriptions of neurological and psychiatric disorders, emphasizing their historical significance in medical history.

This article examines a rare silent film created by Samuel Alexander Kinnier Wilson in the 1920s, depicting patients with movement disorders such as Parkinson’s disease, Huntington’s chorea, and Wilson’s disease.

This study maps neuroanatomical changes throughout human pregnancy, revealing widespread alterations in brain structure, including decreases in gray matter volume and increases in white matter integrity.

This study reveals that individuals with depression exhibit an expanded frontostriatal salience network. The expansion is stable over time and may serve as a trait-like marker for depression risk.

This 10-year follow-up study examines clinical recovery and treatment resistance in individuals with first-episode psychosis. It identifies early-course predictors of long-term outcomes, emphasizing the importance of early intervention.

This article reviews the neurobiological underpinnings of PTSD and discusses current and emerging treatment approaches, highlighting the importance of personalized interventions.

This comprehensive report by the Lancet Commission provides updated evidence on dementia prevention, intervention, and care. It identifies 14 modifiable risk factors across the life course, suggesting that up to 45% of dementia cases could be prevented or delayed. The report emphasizes the importance of early-life education, midlife and late-life...

Abstract
Aleksandr Luria repeatedly emphasised the importance of emotions and the right hemisphere
in his neuropsychological writings. It is surprising, therefore, that Luria's most
influential book, The Working Brain, appears to lack an explicit section on these topics. This
is especially notable because of a comment...

This systematic review analyzes fMRI studies of self-processing in schizophrenia, providing new insights into altered brain function and its implications for diagnosis and treatment.

This study investigates the neural mechanisms of electroconvulsive therapy (ECT) in major depressive disorder (MDD). Findings suggest that increases in aperiodic activity, rather than traditional EEG slowing, better explain clinical improvements post-ECT.

This study investigates factors predicting the transition from major depression to bipolar disorder using data from a Swedish national longitudinal cohort. The findings highlight early age of onset as a significant risk factor for conversion, while the role of sex remains inconclusive. The study emphasizes the importance of early identification...

This comprehensive review explores the neuropsychiatric manifestations of long COVID, including cognitive impairments, mood disturbances, and fatigue. It discusses potential mechanisms, diagnostic challenges, and therapeutic approaches, emphasizing the need for multidisciplinary care.

This report discusses the neuropsychiatric manifestations of postacute sequelae of COVID-19 (PASC), including cognitive impairments, mood disturbances, and fatigue. It emphasizes the need for comprehensive neuropsychiatric evaluation and multidisciplinary care approaches for affected individuals.

This comprehensive review outlines a structured diagnostic approach to adult-onset neurometabolic diseases, emphasizing clinical presentations, biochemical markers, neuroimaging findings, and the importance of early recognition for effective treatment.

This study reports a novel mutation in the optineurin (OPTN) gene associated with aggressive amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). The findings expand the genetic spectrum of ALS/FTD and suggest that OPTN mutations can lead to rapidly progressive neurodegenerative phenotypes.

This article explores the historical development of the concept of synesthesia during the nineteenth century, examining how perceptions and definitions have evolved over time.

This article discusses Niemann-Pick type C disease, its contemporary diagnosis, and treatment approaches. The condition, a rare genetic disorder, affects lipid metabolism and causes neurological decline. This review article provides an updated overview of Niemann-Pick type C, focusing on its clinical presentation, diagnostic challenges, and evolving treatment strategies. It discusses...

This article traces the historical evolution of neuropsychiatry curriculum, highlighting its foundations in ancient medicine and its development into a modern interdisciplinary field linking neurology and psychiatry.